Police investigating the disappearance of teenager Jayden Parkinson now believe she was murdered.
Jayden, 17, from Oxford, was last seen leaving Didcot Parkway train station at 4.27pm on December 3 - and did not return home that evening as planned.
In a news conference this afternoon, Detective Chief Superintendent Andy Murray revealed that police have upgraded the case to a murder investigation and are looking for a man who was seen in an open field near Upton on December 9 at 2am.
"The father in me would like to think that Jayden is still out there, but I'm afraid the detective in me leads me to conclude that Jayden may well have been murdered," said Mr Murray.
The man spotted in Upton was carrying a large suitcase in the rural area and notably struggling to "manage" the heavy case.
"This man was having difficulty wheeling that suitcase," said Mr Murray.
He said the same man was seen in Didcot around 30 minutes later with the same suitcase, and police are appealing for sightings of the man or the case.
The man is described as a white male in his early 20s, with short dark hair and of medium to slim build.
The case was approximately 3ft long and 2ft wide, likely a pale blue colour, and had an extendable handle and wheels, said Mr Murray.
Police said a recycling bin has been recovered as part of the investigation from the former Crown Pub in Queensway in Didcot.
An address in Abbott Road, Didcot, is also cordoned off by police while a search is carried out on the property.
Thames Valley Police are currently holding two people - a 22-year-old man and 17-year-old boy - in relation to the case.
Police said earlier this week that the 22-year-old was in a relationship with Jayden.
Jayden was living with her mother in Didcot until November this year, when she found herself homeless.
The teenager relocated to an Oxford service called One Foot Forward, which offers assisted and supported accommodation for young people.
Police said Jayden has made no financial transactions, or accessed the internet or her phone since she went missing 12 days ago.
A team of 50 detectives are currently assisting with the case and specialist teams will be scouring the Upton area for the next week.
Anyone with information has been urged to contact Thames Valley Police on 101 and quote URN 542 10/12, or Crimestoppers anonymously on 0800 555 111.
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